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Trial Strokies
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Trial Strokies

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The use of thrombectomy in patients with acute stroke and a large infarct of unrestricted size has not been well studied. We assigned, in a 1:1 ratio, patients with proximal cerebral vessel occlusi%Endovascular thrombectomy for acute ischemic stroke due to medium-vessel occlusion has had varying results across trials. Whether thrombectomy improves functional outcomes in patients with medium-v^Randomized trials have revolutionized acute treatment, prevention, and recovery after stroke since their initial implementation in the 1960s. The first stroke trials included those of antihypertensive medications for primary stroke prevention, 1, 2 aspirin for secondary stroke prevention, 3 and intravenous plasmin for patients with acute ischemic stroke and occlusion of the internal carotid or,STEP is a registry-based trial; it uses data from existing registries to record information for a subset of the trial Case Report Form (CRF). Additional registry data from non-randomized STEP patients may be used for trial screening, planning, and generalizability assessment purposes.@The FASTEST Trial will include approximately 100 hospital sites and at least 15 MSUs in the NINDS-funded StrokeNet and key global institutions with large volumes of ICH patients and the ability to treat them within 120 minutes of stroke onset. We plan to recruit 860 participants over 3½ years.~A Clinical Trial To Evaluate The HeartWare Ventricular Assist System (ENDURANCE SUPPLEMENTAL TRIAL) Rochester, MN This is a prospective, randomized, controlled, unblinded, multi-center evaluation of the stroke incidence in patients implanted with a HeartWare HVAD who receive optimal blood pressure management..This randomized clinical trial examines the safety and efficacy of intravenous alteplase administered 4.5 to 24 hours after stroke onset in patients with salvageable brain tissue.


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